Wyatt et al. (1999)
BMJ
Participants
Meta-analysis of 9 clinical trials
Dosage
50–100 mg B6 daily
Result: Significant improvement in PMS symptoms, especially the emotional ones (irritability, depression).
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For the nervous system and mood
Vitamin B6 (P-5-P)
Pyridoxal 5-Phosphate · Pyridoxal-5-phosphate, the active, coenzyme form of vitamin B6
The active form of B6, the one your body can use directly.
1.4 mgin 1 Corti-Glow sachet
Certificate (COA)
Helps with
PMS irritabilityLow mood before the cycleNervous exhaustionConcentration problems
In plain language
Here's what it does, without complex words.
P-5-P is the active (coenzyme) form of vitamin B6.
Involved in over 100 enzymatic reactions, primarily the synthesis of neurotransmitters.
The body does not store it, it needs to come from food or a supplement every day.
Natural source:
Vitamin B6 is found in chicken, fish, bananas, potatoes, avocado and nuts. P-5-P (pyridoxal-5-phosphate) is the bioactive form, the one the body uses directly. Regular B6 (pyridoxine HCl) must be converted in the liver, a process that isn't efficient in everyone.
Why vitamin b6 (p-5-p) is in Corti-Glow
Every ingredient in Corti-Glow has a specific reason.
B6 is essential for the synthesis of serotonin, dopamine and GABA, the “good” neurotransmitters.
Many women have a mild B6 deficiency, especially under chronic stress or with hormonal contraceptives.
The P-5-P form works in 100% of people, unlike regular B6.
How it works on the body
Mechanism, step by step.
1Serotonin synthesis
B6 is a cofactor in the conversion of tryptophan → 5-HTP → serotonin. Without it, low mood.
2GABA synthesis
Also a cofactor for glutamate decarboxylase, the enzyme that makes GABA (the calm neurotransmitter).
3Estrogen regulation
Helps the liver metabolize excess estrogen, important in PMS.
4Hemoglobin production
Participates in hemoglobin synthesis, directly related to energy and concentration.
What to expect
Realistic timeframes, not promises.
First 2 weeks · Vitamin B6 (P-5-P)
A slight improvement in mood. Clearer thinking.
First 2 weeks
A slight improvement in mood. Clearer thinking.
1 cycle
Less irritability before the cycle. A softer mood.
2–3 cycles
PMS symptoms are visibly milder.
How it works with the other ingredients
7 ingredients in Corti-Glow. Here's the mechanism why they work together.
Not just 7 supplements in one box. Every combination has a specific mechanism, here's why the formula is what it is.
Combination
Vitamin B6 + Myo-Inositol
+ Myo-Inositol · 2000 mg
For cycle and sugar cravings
Mechanism
B6 is a cofactor in the enzymes that synthesize serotonin and dopamine. Myo-Inositol regulates insulin and hormones. Low mood before the cycle comes from two sources, hormonal flux + neurochemistry. B6 tackles the neurochemistry, myo-inositol, the hormonal imbalance.
End benefit
A more stable mood in the luteal phase (the second half of the cycle). Less of an “impossible” week.
3 combinations · click to explore
This is why they aren't sold separately, one sachet, the full chain.
The research
Don't take our word for it, see what the science says.
PubMed
Kashanian et al. (2007)
International Journal of Gynecology & Obstetrics
Participants
94 women with PMS
Dosage
80 mg B6 daily, 3 cycles
Result: Significant improvement in PMS symptoms versus placebo.
Why this exact dose in Corti-Glow
1.4 mg, specific, not random.
- →1.4 mg = 100% of the daily recommended intake (RDA) for adult women.
- →The P-5-P form (not regular B6), active, works in all people regardless of genetic variations.
- →For a therapeutic PMS effect, additional B6 (e.g. 50 mg) may be added standalone, on a doctor's recommendation.
Dose comparison
in mgSee how our dose compares with what was used in clinical trials.
Corti-Glow, our dose
our dose, 1.4 mg
1.4 mg
Wyatt 1999
50–100 mg B6 daily
50 mg
Kashanian 2007
80 mg B6 daily, 3 cycles
80 mg
Corti-GlowClinical study
Frequently asked questions
About vitamin b6 (p-5-p).
Isn't 1.4 mg too little?+
1.4 mg is 100% of the Recommended Daily Allowance (RDA). The high doses (50–100 mg) in trials are therapeutic, for PMS. Our dose is for daily maintenance. If you have severe PMS, consult a doctor about a higher standalone dose.
Why P-5-P instead of regular B6?+
P-5-P is the active form, the body uses it right away. Regular B6 (pyridoxine HCl) has to be activated in the liver, a process that doesn't work well in ~30% of people (genetic variation).
Can there be too much B6?+
Yes, over 200 mg daily for months can cause neuropathy (tingling in the hands/feet). 1.4 mg is a safe dose for daily intake.
Works well with
The other ingredients in Corti-Glow.
For cycle and sugar cravings
Myo-Inositol
2000 mgThe most-studied ingredient for women with PMS (premenstrual syndrome), PCOS (polycystic ovary syndrome) and insulin issues.
See detailsFor bloating and inflammation
Bromelain
100 mgA pineapple enzyme that reduces bloating before your cycle and with water retention.
See detailsVitamin B6 (P-5-P) is one of the 7 ingredients.
Every evening, one sachet with the full formula, at clinical dose.
Save my spotThis information is general and does not replace medical consultation. If you have a diagnosed condition, are pregnant, or are planning pregnancy, consult your doctor before supplements.